EN: Interested in a Nobelprize*? Maybe you should focus on one of the fundamental questions in biology  to get one. PloS Biology started a series of essays discussing these - the Challenges Series. The first essay  is about cooperation.
 Simon A. Levin, DOI: 10.1371/journal.pbio.0040300
 Ned S. Wingreen, Simon A. Levin, DOI: 10.1371/journal.pbio.0040299
* Yup, I know there is unfortunately none for biology ...